Massachusetts Institute of Technology

Poggio Lab

At the Center for Biological and Computational Learning (CBCL), we study the theory of learning under physical, computational, and biological constraints. Using a multidisciplinary approach, we investigate when and how learning is possible to better understand the brain and to build better machines.

Principal Investigator

Tomaso Poggio

Tomaso A. Poggio is a founder of computational neuroscience. He pioneered models of visual perception, bridged neuroscience and machine learning, and helped establish regularization theory and learning theory in vision. His work now focuses on the mathematics of deep learning and visual recognition. He has founded, advised, or invested in multiple technology companies, including DeepMind and Mobileye, and mentored leaders such as Christof Koch, Amnon Shashua, and Demis Hassabis. Poggio is the Eugene McDermott Professor at MIT and former co-director of the Center for Brains, Minds, and Machines. As of 2024, he stands as the largest individual recipient of NSF AI funding over a 14-year period, responsible for over a quarter of all such funding awarded to MIT.

Research Focus

Statistical learning theory and limits of learnability

Foundational research into the mathematical principles of learning and the theoretical boundaries of predictive models.

Generalization and optimization in high-dimensional models

Analyzing how complex neural networks generalize and the optimization dynamics in high-dimensional parameter spaces.

Deep learning and alternative training paradigms

Exploring novel architectures and training methods that move beyond standard approaches to improve efficiency and robustness.

Learning principles shaped by biological constraints

Investigating how biological systems process information to derive principles for human-like machine intelligence.

Researchers

Our students and visiting researchers have expertise in physics, computer science, cognitive psychology, and complexity theory.

View past members
Dr. Tomaso A. Poggio

Dr. Tomaso A. Poggio

Researcher

Qianli Liao

Qianli Liao

Researcher

Pierfrancesco Beneventano

Pierfrancesco Beneventano

Researcher

Daniel Mitropolsky

Daniel Mitropolsky

Researcher

Marc Gong Bacvanski

Marc Gong Bacvanski

Researcher

Yulu Gan

Yulu Gan

Researcher

David Koplow

David Koplow

Researcher

Lorenzo Rosasco

Lorenzo Rosasco

Researcher

Liu Ziyin

Liu Ziyin

Researcher

New Seminar Series

AI: Foundations for Academia (and Startups)

The landscape of AI research is shifting. Many problems that once defined academia are now dominated by scale, data, and incumbent advantage. Yet the most important questions remain open. What are the fundamental principles of intelligence, and how can they guide systems that learn efficiently, generalize robustly, and create real societal and economic value? This seminar argues that academia remains the place to identify and test principles of intelligence. Startups remain the place to turn those principles into systems that matter. We convene the MIT-area community to identify foundational principles that are shared by biological and artificial intelligence, and translate them into deployable, venture-scale technologies. We will connect empirical evidence from cognitive development, systems neuroscience, and modern AI systems with formal structure in learning and reasoning, including sample efficiency, sparse compositionality, invariances, memory, optimization dynamics, and generalization. By the end of the series, we will have identified and tested key conjectures about intelligence and built new collaborations between labs and startups.

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